Fahime Majlesi - Ghadr Institute of Higher Education, Department of Pharmaceutical Chemistry, Koochesfahan, Guilan
Nosrat O. Mahmoodi - Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box ۴۱۳۳۵-۱۹۱۴, Rasht, Iran.
Atefeh Ghavidast

Nanotechnology is capable of fabricating, controlling, and using nanoscale materials. New science for human life and health has produced many active substances that use these materials, usually because of the inability to transfer them to the desired target at the right time and in the right amount, does not have to be effective. This will cause them to be wasted and unwanted side effects and the re-use of these active ingredients will be required to achieve the desired effect.Surface composition and design of nanoparticles can successfully use In industrial and research fields, such as purification of contaminated water, biological separation, therapeutic and therapeutic applications, and controlled release and targeted drug. Omeprazole, lansaperazole, ropiperazole pantoprazole and pantoprazole sulfide are an selective inhibitor of gastric acid secretion and proton pump inhibitors and irreversibly linked to H + / K + -ATPase (proton pump) and are the strongest inhibitor of gastric acid secretion, as the final phase in Inhibit the acid production cycle. The effect of these drugs is dose-dependent in controlling the secretion of the primary and stimulated stomach acid.Pantoprazole and pantoprazole sulfide are drugs that were studied and tested in this study. To increase the antibacterial properties, they were capped on silver. The synthesis of these nano sized drugs on silver nanoparticle was verified by bacterial testing.

Silver nanoparticles, Pantoprazole, Pantoprazole sulfide, Novel drug delivery, Gastric ulcer, Pantoperazole@AgNPs, Pantoperazole sulfide@AgNPs