Malakoplakia In Association with Adenocarcinoma of Sigmoid Colon, Case Report

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 382

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شناسه ملی سند علمی:

ACPLMED20_115

تاریخ نمایه سازی: 29 تیر 1398

چکیده مقاله:

Background: Malakoplakia is a rare granulomatous disease of genitourinary system.Gastrointestinal tract is the second most common site of involvement. It usually mimics a malignancy but it’s association with adenocarcinoma has been reported rarely. Case presentation: A 59-year-old male patient with history of weight loss and rectal bleeding since two months ago referred to our hospital. Pre-operative CT scan revealed large mass of sigmoid with extension and invasion of serosal surface as well as multiple regional metastatic lymph nodes. With pathologic diagnosis of adenocarcinoma, he underwent sigmoidectomy.On pathologic examination, moderately differentiated adenocarcinoma invading to peri-colic adipose tissue and inflammatory reaction compatible with malakoplakia at the invasive borders of the tumor and extension to serosal surface identified.Conclusion:In patients with gastrointestinal malakoplakia, presence of possible adjacent malignancy should be screened. Possibility of over-staging for adenocarcinoma in association with malakoplakia must be considered as well.

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نویسندگان

Nakisa Niknejad

Hamedan University of Medical Sciences, Besat Hospital,Hamedan, Iran

Fatemeh Nili

Department of pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Mohammad Shirkhoda

Department of surgery, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences