Prevalence of multidrug-resistant Pseudomonas aeruginosa in Amir-Al-Momenin burn hospital

Background: Pseudomonas aeruginosa, a gram-negative pathogen is usually known as nosocomial infections in burn patients. P. aeruginosa can be caused a wast range of infections of surficial skin to fulminant sepsis. The resistance of Antimicrobial is an area of first interest in Pseudomonas infections treatment. The aim of the study was to evaluate and analyses the antibiotic susceptibility pattern of P. aeruginosa isolates from amir-al-momenin burn patients in Shiraz, Iran.Methods: The samples were collected from amir-al-momenin burn Hospital, Shiraz, Iran from 2016-2017. Samples were obtained from different clinical samples who were hospitalized more than 2 days. The Antibiotic susceptibility was established by disk diffusion on Muller-Hinton medium and was carry out matching to the Clinical Laboratory Standard Institute (CLSI) guidelines.Results: Total of 33 P. aeruginosa isolates were collected from wound, sputum, fluid and urine samples. the most isolates were mediate resistance to Co-amoxiclav 25(75.8%) and Resistance rates were high for cefotaxime (CTX) (93.3%), azithromycin (87.9%), gentamicin, ceftazidime, doripenem, imipenem (81.8%) and ciprofloxacin, levofloxacin (78.8%).Conclusions: The results of this research showed antibiotic resistant rate among P. aeruginosa isolates. In our center which can be a forewarning of increasing resistant infections.