The prevalence of virulence genes (papC ،Sfa DE ، afa/dra BC ،fimH، csgA) in E. coli isolates from burn patients with gastroenteritis infection (2016-2017)

Introduction: Pathogenic Escherichia coli cause over 160 million cases of dysentery and one million deaths per year, whereas non-pathogenic E. coli constitute part of the normal intestinal flora of healthy mammals and birds. The morbidity and mortality compared with several recent large earthquakes of gastrointestinal disease caused by Escherichia coli which is highlighted & threat the public health. The goal of this study was to evaluate phylogenetic groups and virulence factors of E. coli causing gastroenteritis infection.Methods: From October 2016 to April 2017, E. coli were isolated from the 70 burn patients with gastrointestinal infection. Polymerase chain reactions were conducted to evaluate the phylogenetic groups and virulence factors (papC ،Sfa DE ،afa/dra BC ،fimH and csgA) in E. coli isolates.Results: None strains belonged to group A, 12.2% related to group B1, 32.1% related to group D, and 55.8% related to group B2. The virulence factors were classified as: papC 21.2%, Sfa D 3.8%, afa/dra BC 25.64%, fimH 98.7% and csgA 94.2%.Conclution: These studies have revealed that Inflammatory Bowel Disease is an incendiary disease of the gastrointestinal tract, and gastrointestinal bacteria have frequently been assumed as the cause of IBD relapses. Attachment by adhesion factor allows bacterial pathogens to communicate with the host cell membrane that has the central role to its pathogenic potential.