Evaluation of the oral probiotic lactofem effect on blood pressure, lipid profiles and glycemic index in overweight pregnant women

  • سال انتشار: 1398
  • محل انتشار: اولین کنگره بین المللی پریناتالوژی، هفتمین کنگره سراسری پریناتالوژی و نئوناتالوژی
  • کد COI اختصاصی: PNMED07_162
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 567
دانلود فایل این مقاله

نویسندگان

S Azima

Department of midwifery, school of nursing and midwifery, Shiraz University of Medical Sciences, Shiraz, Iran

E Gharib

Student Research committee, Shiraz University of Medical Sciences, Shiraz, Iran

M kaviyani

Department of midwifery, school of nursing and midwifery, Shiraz University of Medical Sciences, Shiraz, Iran

T Pordast

Assistant professor of Gynaecology and Obstetrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

چکیده

Background and Objective: The aim of this study was to evaluate the effect of probiotic capsule on blood pressure, lipids and the levels of glycemic indexes.Materials and Methods: In this double-blind, randomized clinical trial, 120 overweigh pregnant women with at 20-week gestational age, were divided into two groups. Individuals in the intervention group (60 women) received daily two probiotic capsules, lactofem, Containing Lactobacillu acidophilus, Lactobacillus plantarum, Lactobacillus fermentum and Lactobacillus gasseri and controls (60 women), daily received two capsules of placebo for 16 weeks until the end of pregnancy. Blood pressure, lipid profiles, Triglyceride (TG), Cholesterol, Low-density lipoprotein (LDL), High-density lipoprotein (HLD), fasting blood glucose and 2-hour post-prandial blood sugar levels were measured, at baseline, 8 weeks after intervention and 16 weeks after intervention. Statistical analyses were done using the SPSS 23 software, the statistical tests being analysis of independent t-test.Results: The results of this study showed significant decreased in systolic and diastolic blood pressure and 2hpp levels in the intervention group compared with the control after 16 weeks of study (P = 0.001 and P = 0.006). However, no significant differences were observed between two groups regarding to fasting blood glucose levels. Significant decrease in cholesterol and LDL serum levels at 8 and 16 weeks were observed.Conclusion: Probiotic capsules, lactofem, may improves the complications of pregnancy associated with blood pressure, lipids and the levels of glycemic indexes in overweight women, which has a higher risk than normal weight women.

کلیدواژه ها

Probiotic capsules lactofem, pregnancy, overweight, glycemic index, blood pressure

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.