Dual-time-point FDG-PET/CT Imaging of Temporal Bone Chondroblastoma: A Report of Two Cases

  • سال انتشار: 1394
  • محل انتشار: مجله پزشکی هسته ای و زیست شناسی آسیا اقیانوسیه، دوره: 3، شماره: 2
  • کد COI اختصاصی: JR_JNMB-3-2_008
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 280
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نویسندگان

Akira Toriihara

Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku, Tokyo, Japan

Atsunobu Tsunoda

Department of Otolaryngology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan

Akira Takemoto

Department of Human Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan

Kazunori Kubota

Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyoku, Tokyo, Japan

چکیده

Temporal bone chondroblastoma is an extremely rare benign bone tumor. We encountered two cases showing similar imaging findings on computed tomography (CT), magnetic resonance imaging (MRI), and dual-time-point 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT. In both cases, CT images revealed temporal bone defects and sclerotic changes around the tumor. Most parts of the tumor showed low signal intensity on T2- weighted MRI images and non-uniform enhancement on gadolinium contrast-enhanced T1-weighted images. No increase in signal intensity was noted in diffusion-weighted images. Dual-time-point PET/CT showed markedly elevated 18F-FDG uptake, which increased from the early to delayed phase. Nevertheless, immunohistochemical analysis of the resected tumor tissue revealed weak expression of glucose transporter-1 and hexokinase II in both tumors. Temporal bone tumors, showing markedly elevated 18F-FDG uptake, which increases from the early to delayed phase on PET/CT images, may be diagnosed as malignant bone tumors. Therefore, the differential diagnosis should include chondroblastoma in combination with its characteristic findings on CT and MRI.  

کلیدواژه ها

temporal bone chondroblastoma, dual-time-point FDG-PET/CT, MRI

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