Regular aerobic training improves insulin resistance but not pancreatic β-cells function in female patients with type 2 diabetes

  • سال انتشار: 1396
  • محل انتشار: فصلنامه فعالیت بدنی و هورمونها، دوره: 1، شماره: 4
  • کد COI اختصاصی: JR_JPAH-1-4_006
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 418
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نویسندگان

Mohsen Omidi

MS in exercise physiology, Marvdasht branch, Islamic Azad University, Marvdasht, Iran

Mehrzad Moghadasi

Associate professor in exercise physiology, Department of exercise physiology, Shiraz branch, Islamic Azad University, Shiraz, Iran

چکیده

Aim: Pancreatic β-cells function and insulin sensitivity resistance were impaired in type 2 diabetes. Exercise training may improves these impairs, however, this is not well known. The aim of present study was to examine the effect of 8 weeks aerobic training on pancreatic β-cells function and insulin resistance in female patients with type 2 diabetes. Material & Methods: Twenty middle-aged women (age, 40 -50 years) with type 2 diabetes participated as the subject. The subjects were randomly assign to control group (n=10) or the training group (n=10). The subjects in the training group performed 30 to 45 min aerobic training on the treadmill with 60-75% of their maximum heart rate, 3 days a week for 8 weeks. The subjects in the control group were instructed to maintain their normal physical activity throughout the study. Results: The results indicated that fasting blood sugar, fasting insulin and insulin resistance index decrease in the training group compare to the control group (P< 0.05); however, pancreatic β-cells function has no significant change after the intervention. Conclusion: In summary, it seems that aerobic training utilized in this study improves glucose entry into cells but it had not effective on pancreatic β-cells function.

کلیدواژه ها

Type 2 diabetes, Aerobic training, Pancreatic β-cells function, Insulin resistance

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