Ultrasonic-Assisted Synthesis and Crystal Structure of a New Di-nuclear Copper (II) Complex

Recently have been reported that metal-organic complexes based on copper,ruthenium and rhodium with N,N -donor ligands such as 2,2 ,-bipyridine or 1,10- phenanthroline acts as an anticancer agent more effective than cis-platinum[1, 2]. The complexation of transition metal ions such as Cu(II) with pyrazolone derivatives, causes them to be used as active agents in biological, pharmacological and clinical. In this study, a dinuclear copper (II) complex with a formula of [Cu2(pydc)2(inta)2(H2O)2] .3H2O (Fig.1) have been synthesized under ultrasound irradiation and characterized using various techniques such as (SC- XRD), FT-IR spectroscopy, UV–Visible spectroscopy and thermal analysis methods (TGA and DSC). The two Cu(II) centers have different coordination number and geometry. One of the centers is six-coordinate with a distorted octahedral geometry and another one is penta-coordinate with a distorted square pyramidal. The two centers of copper are coordinated to each other through one μ-carboxylate oxygen of pydc ligand.