Effect of marker density and trait heritability on the accuracy of genomic prediction over three generations
- سال انتشار: 1393
- محل انتشار: دوفصلنامه علوم و فناوری دامداری، دوره: 2، شماره: 2
- کد COI اختصاصی: JR_KLST-2-2_008
- زبان مقاله: انگلیسی
- تعداد مشاهده: 398
نویسندگان
Department of Animal Science, Shiraz University, Shiraz, Iran.
Department of Animal Science, Shiraz University, Shiraz, Iran.
Department of Animal Science, Shiraz University, Shiraz, Iran.
Department of Animal Science, Shiraz University, Shiraz, Iran.
چکیده
The aim of this study was to determine the effect of marker density, level of heritability, number of QTLs, and size of training set on the genomic accuracy over three generations. Thereby, a trait was simulated with heritability of 0.10, 0.25 or 0.40. For each animal, a genome with 20 chromosomes, 1 Morgan each, was simulated. Different marker densities (2000, 4000 and 6000 markers) and 400 and 600 randomly distributed QTLs were simulated. Marker density, size of training set, and heritability level significantly affected the genomic accuracy (P< 0.05). Increasing the marker density from 4000 to 6000 did not affect the genomic accuracy, likewise there was no difference between genomic accuracy of the first, and second validation sets (generations 8 and 9). The results showed that 4000 markers may be appropriate for genomic evaluation, and that the estimated marker effects can be used for at least two subsequent generations although the marker effects should be re-estimated for the third generation.کلیدواژه ها
marker density, heritability, genomic breeding valueاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.