A genome-wide scan to detect signatures of recent selection in Australian Merino sheep
- سال انتشار: 1396
- محل انتشار: دوفصلنامه علوم و فناوری دامداری، دوره: 5، شماره: 2
- کد COI اختصاصی: JR_KLST-5-2_008
- زبان مقاله: انگلیسی
- تعداد مشاهده: 412
نویسندگان
Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, ۷۶۱۶۹-۱۳۳, Iran. | Young Researchers Society, Shahid Bahonar University of Kerman, Kerman, Iran.
Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, ۷۶۱۶۹-۱۳۳, Iran.| Honorary Associate, School of Environmental and Rural Science, University of New England, Armidale, NSW ۲۳۵۱, Australia.
Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, ۷۶۱۶۹-۱۳۳, Iran. | State Key Laboratory of Genetic Resources and Evolution, Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming
Animal Genetic and Breeding Unit, University of New England, Armidale, NSW ۲۳۵۱, Australia.
چکیده
Domestication and selection are processes that conserve the pattern of genetic diversities between and within populations. Identification of genomic regions that are targets of selection for phenotypic traits is one of the main aims of research in animal genetics. An approach for identifying divergently selected regions of the genome is to compare FST values among loci to estimate the genetic variability between and within populations. In this study, a whole genome scan using the 50K Illumina Ovine SNP chip was performed in seventeen flocks of Australian Merino sheep (8 CRC flocks and 9 SG flocks). Population differentiation using FST in these flocks revealed seven genomic regions. These areas were located on chromosomes 2 (two region), 3, 6, 7, 16 and 26 (Wintheta> 0.15). In this study, a number of candidate genes associated with reproductive and growth traits were identified. Study of the reported QTLs in these regions of the ovine and bovine genomes also showed that they associated with important traits such as reproduction, carcass yield, growth and wool traits. Further validation studies of these regions can be used to identify the candidate genes for economically important traits in sheep breeds. The results also provided intuitions for further understanding of the genetic diversities among the Merino flocks.کلیدواژه ها
Australian Merino sheep, genomic scan, population differentiation, signatures of selectionاطلاعات بیشتر در مورد COI
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