Titel; Prevalence and Antibiotic Resistance of Staphylococcus aureus in operation room personnel and its Antibiotic succeptibility patternin Hospitals of Islamic Azad University Mashhad during 2017

IntroductionStaphylococcus aureus is a major pathogen both within hospitals and in the communit and is one of the five most common causes of infections after injury or surgery,and it is one of most resistant non-spore forming bacteria. Most peopleare coloized by Staph aureushntermitently, weras upto 25% have persistent colonization. Carrier state of Staph arueus play a key role in epidemiology and pathogenesis of surgicalwound infection .this study aimed was done to find Staph carrier rate and its Antimicrobial succeptibility in operating room personalMaterial & Methods The type of study was cross sectional which include all operating room personnel of Islamic AzadUniversity Mashhad hospital. 95 inclividu. Samples were taken with sterile cotton swabs from the anterior parts of the nasal . Swabs were plated immediately on to the mannitol salt agar. Suspected colonies were confirmed as S. aureus by Gram staining, catalase, coagulase and DNase tests.. Antimicrobial susceptibility to other antibiotics was performed according to NCCLS guidelines by disc diffusion method and Penichlin,Vancomycin,Cephalothine, ,tetracycline , Erythromycin,Cloxacillin,Genthomycin and methicilin .disks were usedResults individuals were enrollred into study from which 28 (29/47%) were Staph. Resistance to penicillin 95 : and cefotaxine were seen in 93.1% of isolates and all strains were sensitive to vancomycin.and moderate . to gentamicin , tetracycline , erythromycin and cloxacillinConclusion According to the results of this study.high number of operating room staff were resistant to cefotaxime and penicillin, and all strains were sensitive to vancomycin. Therefore, more attention can be paid to adoption of therapeutic and some preventive methods by these antibiotic and also recommended of excessive .prescription of antibiotics is prevention

کلیدواژه ها:

Staphylococcus aureus ، ، Drug Resistant ، operation room