Effects of Stachys lavandulifolia Vahl. on ethanol-induced testicular damages in rats

  • سال انتشار: 1397
  • محل انتشار: بیستمین کنگره ملی و هشتمین کنگره بین‌المللی زیست‌شناسی ایران
  • کد COI اختصاصی: BIOCONF20_021
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 485
دانلود فایل این مقاله

نویسندگان

Siamak Yari

Department of Biology, Faculty of Science, Bu-Ali Sina University, Hamedan, Iran

Roya Karamian

Department of Biology, Faculty of Science, Bu-Ali Sina University, Hamedan, Iran

Mostafa Asadbegy

Department of Biology, Faculty of Science, Bu-Ali Sina University, Hamedan, Iran

Amirhossein Asadbegy

Department of Nursing, Malayer School of Nursing, Hamedan University of Medical Science Hamedan, Iran

چکیده

Ethanol consumption has harmful effects on in the reproductive system of mammals. Oxidative stress plays an important role in ethanol-mediated damages. Stachys lavandulifolia Vahl. (SL) is medicinal plant widely used in Iran folk medicine. SL has strong antioxidative and antiinflammatory effects in various oxidative stress conditions. In this study, it was aimed to examine the effects of SL on ethanol-induced testicular damages. In our study, 24 male Wistar rats were divided into 4 groups: control, ethanol (5 g kg -1) and ethanol (5 g kg -1) + SL (500 mg kg-1) group and SL (500 mg kg-1). After the treatment for 4 weeks, mean seminiferous tubule diameter (MSTD). Johnsen’s mean testicular biopsy score (MTBS) criteria were used for histological evaluation. In addition to sperm parameters including sperm count, motility, viability, and morphology were analyzed. Our data indicate that ethanol administration caused a significant decrease in the sperm count, motility, viability in ethanol group but SL ameliorate this reduction in SL + ethanol group. In this study, both MSTD and MTBS values were decreased in ethanol-treated rats. However, administration of ethanol together with SL resulted in significant improvements in both of these values. In conclusion, our study showed that the reproductive toxicity caused by ethanol may be prevented by SL treatment

کلیدواژه ها

Ethanol, Stachys lavandulifolia, Testis, Rat

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.