Methanol intoxication with cerebral hemorrhage
محل انتشار: کنگره ملی گزارش های موردی بالینی
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 353
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شناسه ملی سند علمی:
CCRMED02_097
تاریخ نمایه سازی: 11 اردیبهشت 1398
چکیده مقاله:
IntroductionMethanol is toxic alcohol which causes central nervous system disturbances ranging from inebriation and drowsiness to obtundation, seizure and coma1. 5-15 ml pure methanol and 10-30 ml methanol 40% will cause neurological and vision problems and death.• Case reportA 46 year-old woman was admitted to the hospital in status of dyspnea, decreased LOC, with history of alcohol drinking and pupils mydriasis. Her vital signs were: PR=45, BP=74/p RR=13, SpO2=85%.She was intubated and prescribed serum Bicarbonate and oral ethanol and Folinic acid She was given panel of blood tests. The results were: PH=6.88, PCO2=51.5, BE=-23.8, HCO3=8.6 (VBG) Urea=16, Cr=1.2, Na=145, K=4.8, Ca=8.4,BS=320. Her admission diagnosis was acidosis due to methanol toxicity so she was sent to emergency hemodialysis. The new records were: PH=7.18, PCO2=22, BE=-18, HCO3=11.4 so Methylprednisolone and Eprex was added to her prescription. According to the patient low consciousness, brain CT scan was ordered after hemodialysis in which bilateral basal ganglia hemorrhage and ICH in right occipital region was revealed. Dialysis was done for times, till acidosis resolved. Then she was referred to ophthalmology consultation to check the involvement of optic nerve which confirmed bilateral Marcus Gunn involvement and disc hyperemia and edema. At last Insulin therapy was started due to high blood glucose level (hyperglycemia).• DiscussionSelective toxicity of the optic nerve and basal ganglia and bilateral putaminal necrosis are some of methanol intoxication complications. Cerebral hemorrhage is rare complication of methanol intoxication with aggressive clinical course which should be considered during management of such cases.
کلیدواژه ها:
Methanol intoxication Cerebral hemorrhage
نویسندگان
HOORVASH FARAJI DANA
Assistant Professor of Forensic Medicine School of Medicine, Department of Forensic Medicine and Toxicology, Alborz University of Medical Sciences, Karaj, Iran
HANIEH TOGHROLI
Medical Student Student Research Committee School Of Medicine Alborz University Of Medical Sciences Karaj Iran
ALI AHMADI TONEKABONI
Forensic Medicine Specialist School of Medicine Department of Forensic Medicine and Toxicology, Alborz University of Medical Sciences, Karaj, Iran
NAVID KHOSRAVI
Fellowship Of Clinical Toxicology, School of Medicine, Department of Forensic Medicine and Toxicology, Alborz University of Medical Sciences, Karaj, Iran