Synthesis of a new macrocyclic diamide

Macrocyclic diamides have gained a great deal of attention due to their applications in chemistry, Metal separation and molecular recognition and ecology [1]. Due to their capability in selective and effective complexation with variety of transition and heavy metals, molecular ions and Neutral molecules. There is an increasing intrest in the preparation of them [2, 3]. Macrocyclic diamides are valuable intermediates for the preparation of aza crown compounds and more complicated ligands such as cryptands and cryptohemispherands that can be functionalized by Additional ligating centers including chromogenic and proton ionizable groups. In this research work we want to present a new macrocyclic diamide, by reaction of diester with Diethylentriamine. For this research work, we prepared dibenzo sulfoxide, then it was reacted with Methylchloro acetate for preparation of diester, after that, we synthesized macrocyclic diamid, then this product was reduced with Borane. The structure of this new macrocyclic diamide has proved by IR, 1H NMR and 13C NMR.