Assessment of the effect Cinopar (Teriparatide) in the treatment of nonunion bone fractures

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: فارسی
مشاهده: 673

نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

OSAMED26_119

تاریخ نمایه سازی: 21 بهمن 1397

چکیده مقاله:

IntroductionNon-union is a clinical and treatment challenge for surgeons and specialists. Satisfactoryrepair of orthopedic fractures is so important for function and life quality of the patients.A way to achieve this goal is to use systemic treatment. This study aimed to investigate theeffect of Teriparatide on Non-union fractures.Material and MethodsA case series study conducted on 17 patients with Non-union fracture. A radiographicevaluation performed before the intervention. All x-ray images confirmed by a radiologistfor Non-union. Then all the patients underwent -3month treatment with Teriparatide.Finally, a control X-ray image conducted in order to assess the outcome. Data analyzed usingSPSS version 16.ResultsSixteen patients with nonunion fracture were evaluated in this study. Of this patients,nine individuals were male and eight were female. The mean age of the patients was20.51±45.18 years. The mean time past from the accident was 50 weeks. Femoral bonewas the most reported impaired place in our study. Out of the 16 patients who followed,recovery was seen in 10 patients(%62.5) with Cinopar .ConclusionIt is concluded that the treatment with Cinopar was effective to some extent. However,due to the few sample size of the study and also the loss of an accurate orthopedic andradiologic assessment as a nonunion cure index, the efficacy of Cinopar still remains unclear.

کلیدواژه ها:

نویسندگان

Masoud Shayesteh azar

Associate professor of orthopedic surger,Orthopedic Research center, Mazandaran university of medical science, Sari, Iran

Mohammad Hossein Kariminasab

Associate professor of orthopedic surgery, Orthopedic Research center, Mazandaran university of medical science, Sari, Iran

Ghasem Janbabaei

Assistant professor of oncology and hematology, Mazandaran university of medical science, Sari, Iran

Salamn Ghafari

Assistant professor of orthopedic surgery, Orthopedic Research center, Mazandaran university of medical science, Sari, Iran