RELATIONSHIP BETWEEN SERUM ZINC LEVEL AND LIVER ELASTROGRAPHY USING FIBROSCAN IN NON-ALCOHOLIC FATTY LIVER PATIENTS
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 289
نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
INC15_394
تاریخ نمایه سازی: 30 دی 1397
چکیده مقاله:
Background and Aim: Zinc is one of the essential elements for many vital functions of the body, including regulation of gene expression, anti-inflammatory and antioxidant activity, protein and nucleic acids metabolism. Since, many people develop advanced liver disease, including liver cirrhosis, they have zinc deficiency. The aim of this study was to investigate the relationship between liver stiffness and serum zinc levels in patients with non-alcoholic fatty liver disease Methods: This cross-sectional study was performed on 40 non-alcoholic fatty liver disease Patients referring to Imam Khomeini Hospital in Ahvaz in 1395. Serum zinc levels and liver Stiffness (based on METAVIR scale) were measured by fibroscan, and Age, sex, serum zinc level and liver fibroscan were recorded. Serum zinc level at different ages and scores of Liver stiffness was compared and analyzed. Results: This study was conducted on 40 patients with non-alcoholic fatty liver disease. The number of men was 26 patients (65%). Mean age of patients was 45.077±9.4 years, mean serum zinc level was 81.4±8.1 and mean liver stiffness was 6.5±2.1 kPa. Serum zinc level had a reverse and strong correlation with liver stiffness (p=0.0001, r=0.9). Also, with age increasing, liver stiffness increased (p=0.01, r=0.5) and serum zinc level decreased (p=0.01, r=0.5).Conclusion: According to findings of the present study, the serum zinc level significantly decreased with fibrosis progression in patients with non-alcoholic fatty liver and zinc supplementation is beneficial for treatment of NAFLD
کلیدواژه ها:
نویسندگان
Mehrnaz Morvaridi
Research Institute for Infectious Diseases of the Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Eskandar Hajiani
Research Institute for Infectious Diseases of the Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Abazar Parsi
Research Institute for Infectious Diseases of the Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Koroush Erfanian Taghvaie
Research Institute for Infectious Diseases of the Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran