ASSOCIATION OF DIETARY ACID LOAD WITH BODY COMPOSITION AND INFLAMMATORY BIOMARKERS IN PATIENTS WITH TYPE 2 DIABETES

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 357

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شناسه ملی سند علمی:

INC15_316

تاریخ نمایه سازی: 30 دی 1397

چکیده مقاله:

Background and Aim: The higher dietary acid load lead to increasing the risk of diabetes. The aim of this study was to investigate the association between dietary acid load with body composition and inflammatory factors in patients with type 2 diabetes.Methods: A total of 185patients with diabetes were studied, with aged 51.62 years. The food frequency questionnaire, which contains 147 food items, was used to assess dietary intake. Potential renal acid load (PRAL) and Net Endogenous Acid Production (NEAP) was calculated for each person. Inflammatory markers (C-reactive protein, interleukin-6, and TNF-[alpha]) and anthropometric measurements (weight, waist circumference, body weight and body fat (FM)) were measured. Linear regression, Pearson correlation and ANCOVA tests were used to determine the association of dietary acid load with anthropometric measurements and inflammatory factors.Results: The percentage of total body fat (β = 190, p = 0.042) and inflammatory factor TNF-α (Beta = 0.167, p = 0.031) had a positive and significant correlation with PRAL. Total body fat and TNF-a were significant difference among the PRAL tertiles. The percentage of total body fat and TNF_a were higher in two and three tertile, respectively, and this relationship remained significant after adjustment the confounders.Conclusion: The present study showed that PRAL has a positive correlation with body fat and TNF-α.

نویسندگان

Hamed Kordvarkaneh

Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Sakineh Shab-Bidar

Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran