DIETARY APPROACHES TO STOP HYPERTENSION (DASH) AND BREAST CANCER RISK IN A CASE-CONTROL STUDY FROM IRAN

Background and Aim: Breast cancer is the most common cancer among women worldwide. Many studies have focused on diet and breast cancer but few studies have examined associations between DASH diet and breast cancer risk. The purpose of this study was to determine whether adherence to the DASH eating plan is associated with reduced risk of breast cancer.Methods: In a hospital-based case-control study, 134 women diagnosed as breast cancer and 267 controls were recruited from referral hospitals in Tehran, Iran. The DASH scores were calculated for each participant by using dietary information from a validated 168-item food frequency questionnaire.Odds ratio (OR) were estimated using logistic regression.Results: After adjustment for confounders such as age, BMI, first pregnancy age, breast cancer family history and menopausal status , comparing top with bottom quintiles of the DASH score, the OR for breast cancer was 2.64 (95% CI: 1.01, 6.87; P for trend = 0.003).Conclusion: Adherence to the DASH diet (which involves higher intakes of whole grains, fruit, and vegetables; moderate amounts of low-fat dairy; and lower amounts of red or processed meats, desserts, and sweetened beverages) was associated with a lower risk of breast cancer.

کلیدواژه ها:

DASH ، BREAST ، DIET ، CASE-CONTROL