A study of Bacterial Pathogens and Antibiotic Susceptibility Patterns in Chronic Suppurative Otitis Media

Background: Chronic supportive otitis media (CSOM) represents one of the major public health problems. Knowledge of the common causative bacteria of CSOM and their antimicrobial susceptibility profiles is very important for efficient and cost-effective treatment of the patients. This study was performed to assess the frequency of the bacterial causing agents in CSOM and antibiotic susceptibility patterns of isolates among patients. Methods: A total of 185 patients clinically diagnosed as CSOM were interviewed in this study and the middleear effusion samples were collected from the patients using sterile swabs. All the bacterial isolates grown were identified by conventional microbiological methods. Additionally, the antibiotic susceptibility patterns of the isolates were determined by the Kirby-Bauer disk-diffusion. Data were analyzed using the Pearson Chi-Square test in SPSS v.21software. Results: In this study, bacterial growth was seen in 97.3%ofCSOM cases, while five of the samples (2.7%) showed no growth. Staphylococci species (64.9%) were found to be the most prevalent bacteria isolated, followed by Klebsiella species (12.9%) and P. aeruginosa (10.3%). The study indicated that the most effective antibiotic for the treatment of bacterial CSOM was ciprofloxacin. The statistical analysis showed any significant difference in frequency of CSOM patients, their bacterial infestations and antimicrobial susceptibility patterns of the bacterial isolates based on gender as well as age (P> 0.05). Conclusions: Our finding highlights the importance of a continuous and periodic evaluation of the bacteriological profile and antibiotic susceptibility patterns in CSOM patients for efficacious treatment of the infection and to prevent the occurrence of complications.

کلیدواژه ها:

Chronic supportive otitis media ، Bacterial isolates ، Antibiotic susceptibility ، Ear discharge