The future of personalized medicine in cancer therapy

Conventional medicine originated from empirical treatments and gradually evolved to mechanism-based treatments. Improvements in understanding of molecular basis of diseases which is deeply indebted to whole genome sequencing program, forms the genetic medicine. Further improvements in different fields like system biology and pharmacology alongside of genetic medicine builds the basis of personalized medicine. Personalized medicine, enables to tailor specific therapy to each patient by considering the gene makeup and biomarkers which is specific to each person and also predicting the complex nature of drug responses beyond patients with the same disorder. The road to personalized medicine for cancer treatment is not linear as the cancer is enormously complex and heterogeneous but the aim in this mission is measuring some key tumor characteristics which inform the optimum therapy regimen tailored for each given patient to successfully treat their cancer and prevent relapse. Although personalized medicine is young and in its beginning steps but in would be capable of being a tool to detect, manage and prevent diseases in primary stages and this depends on its progress in area such as ongoing genomic project, merging translational medicine with personalized medicine, increasing advance toward personal genetic testing and the observed evolution of conventional medicine to personalized medicine in the future.

کلیدواژه ها:

personalized medicine ، pharmacogenetics ، cancer