Synthesis of Potassium Exchange Membrane by Clindamycin Antibiotic

Ionophores are moderate molecular weight compounds that are mobile ion carriers. Because ionophores are highly lipophilic, they rapidly dissolve into bacterial cell membranes. Ionophores bind ions, shield the ionic charges and translocate ions across the bacterial membrane, disrupting crucial ion gradients [1]. The first neutral ionophores used in ISE membranes were antibiotics.They were followed by a large number of natural and synthetic, mainly uncharged carriers for cations and a series of charged and uncharged ones for anions [2]. The structure of clindamycin raises additional possibilities for its mode of transport. This antibiotic is composed of an amino acid(hygrinic acid) linked to an amino sugar [3]. In this research, we aimed to analysis the amounts of the Clindamycin membrane selectivity with the base of acrylonitrile polymer and the current transition is tested by an aluminium Air battery. The results show a notable current transition. The effect of this method has been examined by FT-IR and XRD analysis.First dissolve poly acrylonitrile with some DMF solution on a magnetic stirrer. Then add some Clindamycin powder. In order to slick the solution, put them into an ultrasonic bath for some minutes. After that pour the solution on a flat glass and put it into an oven with 90C˚ to be dried.

کلیدواژه ها:

Potassium exchange membrane ، Clindamycin ، ionophore ، poly acrylonitrile