Sepideh Khodaverdi - Endometriosis Research Center, Department of Obstetrics and Gynecology, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Fariba Almassi Nokiani - Minimally Invasive Surgery Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Soheila Amini-Moghaddam - Endometriosis Research Center, Department of Obstetrics and Gynecology, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Neda Hashemi - Endometriosis Research Center, Department of Obstetrics and Gynecology, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Background: It has been shown that Carbohydrate antigen (CA) 125 and CA 19-9 tumor markers are useful for diagnosis and follow up of ovarian carcinoma. Case: In this case, we reported the high level of CA-125 and CA 19-9 with large right ovarian intact endometrioma and extensive involvement of omentum. Conclusion: Human Epididymis protein (HE4) and Risk of ovarian malignancy algorithm (ROMA) can be useful in differentiation between malignancies and benign pathologies with a good sensitivity and specificity value.

Human epididymis protein 4 (HE4), Risk of ovarian malignancy algorithm (ROMA)