THE PREVALENCE OF RESPIRATORY VIRUSES IN IRANIAN CHILDREN WITH ASTHMA
- سال انتشار: 1397
- محل انتشار: نوزدهمین کنگره بین المللی میکروب شناسی ایران
- کد COI اختصاصی: MEDISM19_599
- زبان مقاله: انگلیسی
- تعداد مشاهده: 444
نویسندگان
kermanshah university of medical sciences
kermanshah university of medical sciences
kermanshah university of medical sciences
چکیده
Background and Aim:Our aim in this study, was evaluation of the viral infections prevalence in the children with asthma in 2016 to 2017. Viral infections induce NF-kB activation and inflammatory pathways that led to produce cytokines, chemokines, inflammatory proteins, and finally reduce lung volume and function disorder Asthma is a chronic inflammatory of the lung airways that about 300 million people suffering from the disease worldwide.Methods:Materials and Methods: One hundred throat swab sample were collected from children with asthma. RNA extraction and cDNA synthesis were done for frequency determination of parainfluenza viruses, rhino virus, influenza and respiratory syncytial virus (RSV) using Real Time PCR.Results:41 positive cases were detected including 21 cases of rhinovirus (51.22%), 10 cases of parainfluenza (24.39%), 7 cases of respiratory syncytial virus (17.07%) and 3 cases of influenza virus (7.32%). However, there was no significant statistical relationship between the frequency of viruses with the age and gender of patientsConclusion:The most important cause of asthma in this study was rhinovirus. Parainfluenza was most commonly reported in children after rhino virus. The lowest prevalence is related to RSV and influenza virus. The two viruses also showed the least seasonal outbreaks in the studiesکلیدواژه ها
Asthma, Respiratory viruses, Inflammationاطلاعات بیشتر در مورد COI
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