THE EFFECT OF ANTIBACTERIAL POLYVINYL ALCOHOL/FE3O4@CARBON NANOTUBES NANOCOMPOSITE AGAINST PSEUDOMONAS AERUGINOSA

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 284

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شناسه ملی سند علمی:

MEDISM19_385

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:Burn wound is a suitable site for infections and drug resistant P. aeruginosa is the most common bacteria causing these infections. Therefore, research on finding effective drugs seems to be necessary. The aim of this study was to determine antibacterial bio-Nano-bio-organic structures on the burn wound infections due to P.aeruginos.Methods:In this research study, the polyvinyl alcohol/Fe3O4@carbon nanotubes (PVA/Fe3O4@CNTs) nanocomposite was prepared by electrochemical-assisted synthesis method, characterized by FT-IR, UV–vis, FE-SEM, TEM, BET and XRD techniques, and subsequently applied for the ultrasound-assisted removal of methylene blue (MB) dye from aqueous solution and as antibacterial agent in vitro investigation against Pseudomonas aeruginosa (PAO1) bacteria by MIC, MBC, ZOI metodes.Results:PVA/Fe3O4@CNTs at the concentration of 50 mg/ml showed the highest inhibitory effect on the growth of P. aeruginosa, whereas, at the concentration of 200 mg/ml the most lethal effect were observed.Conclusion:Overall, the results of the study showed that the PVA/Fe3O4@CNTs have antimicrobial properties against P. aeruginosa. Therefore, using them in the treatment of infections caused by these bacteria is useful and also be used as disinfectant.

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نویسندگان

Hadis Hassanvand

Cellular and Molecular Research Center, Yasuj University on Medical Sciences, Yasuj, Iran

Vahideh Pezeshkpour

Cellular and Molecular Research Center, Yasuj University on Medical Sciences, Yasuj, Iran

Farzaneh Fasihi

Cellular and Molecular Research Center, Yasuj University on Medical Sciences, Yasuj, Iran