COMPARISON OF THE ANTIFUNGAL ACTION POTENCY OF TEUCRIUM POLIUM L. AND AMPHOTRICIN B AGAINST CANDIDA PARAPSILOSIS

Background and Aim:Teucrium species have been used in traditional medicine for treatment of different diseases. The mechanism of antifungal action potency of Teucrium polium L. and amphotricin B against candida parapsilosis was investigated in this study.Methods:plant was collected from Isfahan during the spring and the mechanism of antifungal activity of Teucrium polium was studied. Candida parapsilosis was added to ethanolic extract in tubes, then presence of sodium, potassium, glucose and amino acids in the tubes was examined by flame photometer, autoanalyzer, and HPLC.Results:Results showed that sodium, potassium, glucose and amino acids were releasd from Candida parapsilosis.Conclusion:According to the result, the antifungal activity of Teucrium polium is similar to Amphotricin B.

کلیدواژه ها:

Teucrium polium ، Candida parapsilosis ، flame photometer ، autoanalyzer ، and HPLC