THE COMPARISON OF ZOUSH OINTMENT WITH AKBAR 1 OINTMENT IN BURN WOUND INFECTION

Background and Aim:Pseudomonas aeruginosa is a gram negative and pathogen bacilli that causes high mortality in immunocompromised patients. It is also the third leading cause of nosocomial infections, and is the second most common pathogens in burn wounds.(1) So we decided to formulated natural ointment can inhibit Pseudomonas aeruginosa’s infection in burn patient.Methods:ZOUSH ointment was formulated with natural ingredients. In 80 mice, burn was induced by Ian Allen Holder. Two treatments per day and 20 days with Akbar 1 and ZOUSH ointment were performed in two separate groups.Results:In the treatment group with Akbar 1 ointment, the average number of isolated Pseudomonas aeruginosa is declining, but this decrease was much lower than the ZOUSH ointment treatment. The mean number of Pseudomonas aeruginosa isolated in treatment with Akbar 1 ointment after 20 days of treatment is approximately equal to 10 days of treatment with ZOUSH ointment. In the ZOUSH ointment group, during the treatment, the mean number of isolated Pseudomonas aeruginosa was not only reduced, but the mean number of Pseudomonas aeruginosa isolated after 20 days of treatment was zero. However, this result was not achieved in the treatment groups of Akbar 1 ointment. These results also indicate the beneficial effect of bactericidal ZOUSH ointment compared to Akbar 1 ointment.Conclusion:Our results indicate that bactericidal has a ZOUSH ointment with an effect more than double, the Akbar 1 ointment.

کلیدواژه ها:

ZOUSH ointment ، Akbar 1 ، wound infection