OCCURRENCE OF THE METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AMONG RESPIRATORY TRACT SAMPLES IN PATIENTS ADMITTED IN IMAM REZA HOSPITAL, BOJNURD, IRAN IN 1396

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 445

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شناسه ملی سند علمی:

MEDISM19_142

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:: Staphylococcus aureus is one of the major pathogens. Methicillin-Resistant Staphylococcus aureus (MRSA) is responsible for an increasing number of serious nosocomial and community acquired infections including superficial lesions and wound infections, osteomyelitis, endocarditis, pneumonia, bacteremia, Toxic shock syndrome and food poisoning. The purpose of this study was to define the prevalence of MRSA strains among S. aureus strains isolated from Respiratory tract samples of patients of selected Tehran hospitals with conventional and molecular methods.Methods:A total 55 isolates from Respiratory tract samples were evaluated by disk diffusion and MIC agar dilution tests according to the guidelines of the Clinical Laboratory Standards Institute (CLSI) and PCR assay for mecA gene.Results:Prevalence of MRSA strains were %50 with disk diffusion method, %51.74 with MIC method and %50.9 using PCR method for detection of mecA gene. Also the drug resistance for other antibiotics of isolates was to Rifampin (%26.66), Penicillin (%100), Vancomycin (%0), Co-trimoxazole (%47.27), Gentamycin (%58.18), Tetracycline (%67.27), Erythromycin (%65.45), Ciprofloxacin (%50.9), Amikacin (%49.09) and Doxycycline (%34.54).Conclusion:our results show relatively good correlation between phenotypic and genotypic methods for antibiotic susceptibility tests. These differences were not statistically significant (P> 0.05). It’s necessary to stablish a solution for control and suitable treatment of the MRSA isolates and prevention of hazardous epidemy.

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نویسندگان

Zahra AliAbadi

B.Sc of Laboratory Sciences, Food and Drug Laboratory, North Khorasan University of Medical Sciences, Bojnurd, Iran

Mahsa Mirzaei

B.Sc of Laboratory Sciences, Food and Drug Laboratory, North Khorasan University of Medical Sciences, Bojnurd, Iran

Mahsa Khosrojerdi

M.D, Specialist in Pediatrics, Department of Pediatrics, Faculty of Medicine, Semnan University of Medical Sciences and Health Services, Semnan, Iran