Fertility Preservation in Patients with Prostate Cancer

Backgound: Prostate cancer is the first men s cancer, with 1288 cases for 100,000 people per year. An increasing number of younger men are diagnosed each year with prostate cancer and data have shown that sexual function is highly important to this younger cohort. These men are sufficiently young that future fertility could be an issue for them, all the more, it is a tendency to have children later in life. Different approaches are available for these kind of patients to preserve fertility.Methods: A literature review on prostate cancer and fertility over the last 10 years was carried out on PubMed database. The literature was based on evidence and practical considerations. Thirteen research articles were selected according to their relevance. Results: Several approaches such as total prostatectomy, external radiotherapy, prostate brachytherapy, hormonotherapy, chemotherapy, active surveillance, sperm preservation, and focal therapy could be implemented on prostate cancer patient. It is worth mentioning that although different therapeutic methods are developed for targeting dysfunctional prostate in order to keep fertility of the patients, their adverse side effects are should not be ignored. Conclusion: In the era of prostate-specific antigen screening, some of the patients diagnosed with prostate cancer still want to maintain their reproductive abilities. All the management options for prostate cancer that mentioned would be harmful for men s fertility. However, fertility options and potential counseling should be part of the routine pretreatment appointments for men undergoing treatment of prostate cancer.

کلیدواژه ها:

Fertility Preservation ، Sperm Preservation ، Prostate Cancer