A study on Antibacterial Effects of lavendula Essential oil on Drug Resistant Pseudomonas aeruginosa Isolates in Golestan province

Background and objective : Pseudomonas aeruginosa is an opportunistic bacterium and is one of the main causes of infection in burn patients.This study aims to determine the antibacterial effects of Lanandula essence on the growth of drug-resistant strains of Pseudomonas aeruginosa.Methods: This descriptive study was carried out on 09 patients that hospitalized in Golestan province Hospitals . Culture methods and diagnosis tests were used to separate and diagnose Pseudomonas aeruginosa, and disk diffusion agar method with the Kirby-Bauer standard was applied to determine the pattern of drug-resistance. The antibacterial effect and the minimum inhibitory concentration (MICs) of lavandula were determined by broth microdilution test . Results : In this study, 35.43 strains were diagnosed as Pseudomonas aeruginosa, out of which %9.903 showed resistance to Ceftazidime, %9.. 43 to Tobramycin & Cefepime, 99.573 to Gentamicin , 99.0%3 to Piperacillin and 99.0. 3 to Norfloxacin. In the present study, the MIC of lavandula against Pseudomonas aeruginosa was determined at 5-7925µl/ml, in which the most growth fluctuations it had were seen in the densities of 472 and 24. µl/ml. Also, No growth was also observed in the densities of 7925µl/ml and higher .Conclusions:Spread of P.aeruginosa resistant to agents is very high in hospitals, and lavandula essence proved anti-bacterial effects while considerable difference was seen between the strains sensitive and resistant to antibiotics .

کلیدواژه ها:

Pseudomonas aeruginosa ، Drug resistance ، Lavandula ، Essence