Developmental vs. Epileptic Encephalopathies
عنوان مقاله: Developmental vs. Epileptic Encephalopathies
شناسه ملی مقاله: CDDMED01_002
منتشر شده در همایش اختلالات تکاملی کودکان در سال 1397
شناسه ملی مقاله: CDDMED01_002
منتشر شده در همایش اختلالات تکاملی کودکان در سال 1397
مشخصات نویسندگان مقاله:
Mahmoud MOHAMMADI - Pediatric Neurology and Clinical Neurophysiology, Department Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
خلاصه مقاله:
Mahmoud MOHAMMADI - Pediatric Neurology and Clinical Neurophysiology, Department Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Developmental disorders and epilepsy are quite common in pediatric patients. For many encephalopathies, there is a developmental component independent of the epileptic encephalopathy. Developmental delay may sometimes precede seizure onset. Co-morbidities e.g. cerebral palsy, autism spectrum disorder, intellectual disability may be seen in epileptic children. In some conditions such as KCNQ2, STXBP1 encephalopathies, outcome is poor even though seizures stop.Epileptic activity itself contributes to severe cognitive and behavioral impairment above and beyond that expected from the underlying pathology and that these can worsen over time. There are some differentiating features between developmental and epileptic encephalopathies such as developmental encephalopathies may begin in utero or after birth. Epileptic encephalopathies can occur at any age and may have some remediable component such as choosing right vs wrong antiepileptic medications. We addressed some of developmental disorders in patients referred to our epilepsy center at Children’s Medical Center and discussed with them.
کلمات کلیدی: Epileptic encephalopathy; developmental encephalopathy;pediatric epilepsy center; KCNQ2 encephalopathy; STXPB1 encephalopathy
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/739437/