The use of serum ca-125 and its prognostic value for prediction of ovarian endometrioma (OMA )and Deep Infiltrative Endometriosis (DIE)

  • سال انتشار: 1396
  • محل انتشار: سومین کنگره بین‌المللی تولیدمثل
  • کد COI اختصاصی: ISERB03_085
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 439
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نویسندگان

Khadijeh Shadjoo

Reproductive Immunology Research Center ,Avicenna Research Institute, ACECR, Tehran, Iran Endometriosis and Pelvic Pain Clinic, Avicenna Infertility Clinic, Avicenna Research Institute, ACECR, Tehran, Iran

Arash Mohazzab

Reproductive Immunology Research Center ,Avicenna Research Institute, ACECR, Tehran, Iran Endometriosis and Pelvic Pain Clinic, Avicenna Fertility Center, Avicenna Research Institute, ACECR, Tehran, Iran

Roya Padmehr

Reproductive Immunology Research Center ,Avicenna Research Institute, ACECR, Tehran, Iran Endometriosis and Pelvic Pain Clinic, Avicenna Fertility Center, Avicenna Research Institute, ACECR, Tehran, Iran

Parvin Jaberi-Pour

Reproductive Immunology Research Center,Avicenna Research Institute, ACECR, Tehran, Iran Endometriosis and Pelvic Pain Clinic, Avicenna Fertility Center, Avicenna Research Institute, ACECR, Tehran, Iran

چکیده

Background: The purpose of this study was to estimate the prognostic value of serum ca-125 level for prediction of ovarian endometrioma (OMA) and deep infiltrative endometriosis (DIE) and their severity .Methods: 230 patients who had undergone laparoscopic surgery and diagnosis of endometriosis and DIE were confirmed by pathology. This study was performed in Avicenna Endometriosis Clinic between years 2012-2014. CA-125 serum levels were measured preoperatively by electrochemi-luminescence . Normal cut off value of ca125 was 35 unit/ml. Patients were categorized by endometriosis involvement (+,-) also type of the disease (OMA and DIE) .r-ASRM endometriois score and its component was considered as severity of each type of lesions.Result: From 173 patients diagnosed with endometriosis , 106 patients (61.2 %) had DIE and OMA, 35 patients ( 20.2 %) had OMA, and 32 patients (18.4%) were involved by DIE . 57 patients were categorized in non-endometriosis groups (control).The χ2 test showed significant relationship between OMA and ca125 (OR=8.48 ,P-values Conclusion: This study enhances the prognostic value of ca-125 . it seems OMA is predicted better than DIE by ca125, but high levels of serum ca-125 have equal value for prediction of severity of OMA and DIE.

کلیدواژه ها

Deep infiltrating endometriosis, Endometrioma, Endometriosis, Ca-125

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