Tribulus terrestris extract improves human sperm parameters in vitro
- سال انتشار: 1396
- محل انتشار: سومین کنگره بین‌المللی تولیدمثل
- کد COI اختصاصی: ISERB03_058
- زبان مقاله: انگلیسی
- تعداد مشاهده: 453
نویسندگان
Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Infertility Treatment Research Center, Moatazedi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
چکیده
Background: T. Terrestris (Tribulus terrestris) is a medicinal plant which is used in treatment of various disorders such as male infertility. The object of the present study was to investigate the in vitro effects of direct addition of T. Terrestris extract on human sperm motility, viability and DNA fragmentation.Methods: Semen specimens from 40 healthy men volunteers were divided into four equal groups: one was as-received with no treatment (control group) while the others were incubated with 20, 40 and 50 μg/ml of T. Terrestris extract (experimental groups). Sperm motility, viability and DNA fragmentation were checked after 0, 15, 30, 60 and 120 minutes for all the groups. Motility and viability were assessed according to WHO criteria.Result: The results of the experiments showed that the incubation of human semen with 40 and 50 μg/ml of T. Terrestris extract (groups 3 and 4) for 0 and 30 min holding time had no effect on total sperm motility, number of progressive motile spermatozoa and curvilinear velocity, whereas, these parameters were significantly enhanced over 60 to 120 min holding time (P < 0.05 or < 0.01). Furthermore, viability was significantly enhanced by using T. Terrestris extract (P < 0.01).Conclusion: In vitro addition of the T. Terrestris extract to human sperm could improve the male fertility capacity.کلیدواژه ها
DNA fragmentation, Human sperm, Motility, Viability, T. Terrestrisاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.