Can Methylene Blue Dye be as an alternative of Patent Blue Dye in finding Sentinel Lymph Node in Breast Cancer Surgery
- سال انتشار: 1394
- محل انتشار: یازدهمین کنگره بین المللی سرطان پستان
- کد COI اختصاصی: ICBCMED11_054
- زبان مقاله: انگلیسی
- تعداد مشاهده: 562
نویسندگان
Endoscopic and Minimally Invasive surgery Research Center, Department of surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Nuclear Medicine Research Center, Department of nuclear menicine ,Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Endoscopic and Minimally Invasive surgery Research Center, Department of surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده
Introduction: We evaluate detection rate and local complications of methylene blue (MBD) in comparison of patent blue dye (PBD) for Sentinel Lymph Node (SLN) biopsy in early breast cancer patients. Methods: In a cohort prospective study on 312 patients, divided in two group base on a kind of blue dye, we filled out a check list for the patients with demographic data, size of tumor, stage, detection of sentinel lymph node and complications and then analyzed the data. Results: Mean tumor size was 2.4 cm. Detection rate was in MBD group 77.5% with dye alone and 94.2% with dye and radioisotope; in PBD group it was 80.1% and 92.9% respectively. We had blue discoloration of the skin in 23.7% in PBD group and 14.1% in MBD that was significantly lower and also local inflammation in 1 patient in PBD group and 5 in MBD that was significantly higher. We did not have skin necrosis and systemic. Conclusion: Methylene blue is less expensive and has acceptable detection rate and low complications comparing Patent blue.کلیدواژه ها
Breast cancer, Sentinel lymph node, Blue dye, Local complicationمقالات مرتبط جدید
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