Treatment of hot flashes in women with breast cancer

breast cancer treatments are very effective but may induce adverse events such as premature menopause. Most patient experience menopausal symptoms such as hot flashes. This symptom is the major complaint during treatment. Given that hormone therapy is contraindicated inthese patients, and the use of non-hormonal therapies is recommended for these patients. Therefore the aim of this study was review the treatment of hot flashes in breast cancer patients. Methods: To get the purpose of this study, we investigation related articles in pubmed, science direct and google scholar by entering keywords, hot flash , vasomotor symptoms , treatment and breast cancer separately and combined. And related articles have been reviewed and evaluated. Results: The studies showed that serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, antihypertensives and anticonvulsants significantly reduced the number and severity of hot flashes in this patient.Conclusion: Medications such as venlafaxine, paroxetine, citalopram, clonidine, gabapentin and Pregabalin can be used for treatment of hot flashes in women with breast cancer. It should be noted, the use of Fluoxetine and Paroxetine in patient being treated with Tamoxifen is not recommended, because reduce the efficacy of Tamoxifen. Black cohosh and phytoestrogens and sertraline will have little impact for treatment of hot flashes in these patients