The Effect of Intravenous Infusion of Magnesium Sulfate During Bimaxillary Orthognathic Surgery on Post-operative Pain: A Clinical Trial
- سال انتشار: 1395
- محل انتشار: مجله علمی جراحی، دوره: 3، شماره: 1
- کد COI اختصاصی: JR_AJS-3-1_006
- زبان مقاله: انگلیسی
- تعداد مشاهده: 602
نویسندگان
Department of Craniomaxillofacial Surgery, School, of Dentistry, Shiraz university of medical Sciences, Shiraz, Iran
Department of Craniomaxillofacial Surgery, School, of Dentistry, AND Health Policy Research Center, Shirza University of Medical Sciences, Shiraz, Iran
Department of Craniomaxillofacial Surgery, School, of Dentistry, AND Shahid Chamran Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: This prospective randomized controlled clinical study aimed to investigate the effect ofmagnesium sulfate (MgSO4) on pain management post orthognathic surgery.Methods: In this study, 52 patients undergoing orthognatic surgery were randomly allocated to receive MgSO4or saline intravenously. The intervention group (n = 26) received intravenous MgSO4 (30 mg/kg bolus for15 minutes immediately before anesthesia induction followed by 10 mg/kg/h dissolved in saline via pumpinfusion) and the second group (n = 26) received the placebo in the same bolus volume as a normal saline in a15 minute intravenous infusion which was continued until the end of the operation. A visual analog scale(VAS) was used to determine the intensity of pain. Invasive arterial blood pressure and valid and invalidanalgesic demand were also recorded. Side effects were recorded, as well.Results: This study was conducted on 52 patients, 26 per group. The results showed no statistically significantdifferences between the two groups with respect to demographics. During the post-operative period, thepatients in the control group showed larger analgesic requirement 7 (26.9%) compared to those in themagnesium group 4 (15.4%) and the difference was not statistically significant (P = 0.308). The post-operativeVAS scores evaluated serially from the recovery room also showed a significant difference between theintervention 3 (11.5%) and the control group 14 (53.8%) after the surgery (P = 0.001). However, no significantdifference was found between the two groups regarding VAS scores in the surgical ward [7 (26.9%) vs. 8(30.8%) P = 0.760].Conclusions: Intra-operative administration of intravenous MgSO4 reduced opioid consumption for pain afterbimaxillary orthognathic operations.© 2014 Tehran University of Medical Sciences. All rights reserved.Citation: Eftekharian HR, Hosseini SAA, Heydari ST. The Effect of Intravenous Infusion of MagnesiumSulfate During Bimaxillary Orthognathic Surgery on Post-operative Pain: A Clinical Trial. Acad J Surg,2016; 3(1-2): 7-11.کلیدواژه ها
Infusions; Intravenous; Magnesium sulfate; Orthognathic surgery; Pain; Post-operative; Pain managementمقالات مرتبط جدید
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