Fabrication and in vitro evaluation of novel nanofiber scaffolds from gum tragacanth/poly (vinyl alcohol)/chitosan for wound dressing application

The aim of present work is design and characterization of a novel nanostructure biopolymer mat for wound dressing applications. Nanofibrous mats based on chitosan (CS), Gum tragacanth (GT) and poly (vinyl alcohol) (PVA), were fabricated by co-electrospining method. Moisture vapor transmission rate of the mat was assessed for a proper wound dressing system using in low and moderate exudate wounds. The mat was also evaluated for cytotoxicity using the methyl thiazolyltetrazolium (MTT) assay which showed biocompatibility of the specimen

کلیدواژه ها:

Gum tragacanth ، Chitosan ، Poly vinyl alcohol ، Wound dressing ، Co-Electrospinning