ELECTROCHEMICAL BEHAVIOR OF SULFONAMIDE DERIVATIVES ON NANO-COMPOSITE MODIFIED CARBON PASTE ELECTRODES

Sulfonamide derivatives that have sulfur and amine groups in their molecular structure areapplied as antibacterial agents. Their residue can reach environment and may cause toxicityand serious public health hazards. As these medications are electro-active, their behavior andconcentration can be monitored by designed electrodes [1-3]. Recently, carbon pasteelectrodes (CPEs) are considered noteworthy due to their valuable properties like low cost,non-toxicity, renewable surface and being able to be modified by wide range of materials.One group of modifiers is nanomaterial. Graphene nano-sheets which are made from graphitemay have not desirable permanence. In order to find better perdurability sheets can befunctionalized by oxygen but this process reduces its conductivity [4]. Chemically reducedgraphene oxide (RGO) that is able to keep conductivity seems more applicable while theproblem of getting restacked still exists. Cerium oxide is an electro-active lanthanide which isnoticeable for electro-catalytic properties. Decorating RGO by cerium oxide NPs can preventNPs from aggregation and RGO nano-sheets from restacking [5]. In this work we studiedelectrochemical behavior of five sulfonamides derivate called sulfadiazine (SDZ),sulfathiazole (STZ), sulfaquinoxaline (SQX), sulfacetamide (SAA) and sulfasalazine (SSZ)on modified CPEs by cyclic voltammetry (CV). In order to optimize the electrochemicalbehavior of mentioned medications on surface of electrodes CeO2 NPs, RGO nano-sheets andRGO decorated CeO2 nano-composite were used as modifiers.