Novel multi walled carbon nanotubes/ionic liquid based carbonpaste electrode for potentiometric determination of analapril in pharmaceuticaland biological fluids

For the first time a novel derivatized multi-walled carbon nanotubes/ionic liquid-based on analapril carbon paste electrodes is reported. At optimum values of variable conditions, theproposed electrodes responded toward analapril linearly in the range of 1.0×10-9 - 5.0×10-3 mol L-1 with slope of 59.58±0.2 mVdecade-1 of analapril concentration and detection limit of 2.0×10-9 molL-1 for ANAL/MWCNTs/I.L-CPE(electrode(17). The electrode response is independent ofpH in the range of 2–8, with a fast response time (10 s) at 25 ◦C for electrode (17). Moreover, the electrodes also showed high selectivity and long life time (more than 8 and 9 weeks) for electrode (17). The electrodes showed good selectivity for enalapril toward wide variety ofspecies. The proposed sensors were successfully applied for the determination of enalapril in pharmaceutical and biological fluids and as indicator electrodes.

کلیدواژه ها:

Potentiometry ، enalapril determination ، multi-walled Carbon nanotube ، ionic liquid ، carbon paste electrode ، Biological fluids