Mehrnoosh Masoumi - Department of textile engineering, Science and Research Branch, Islamic Azad University, Yazd, Iran
Navid Nasirizadeh - Department of textile engineering, Science and Research Branch, Islamic Azad University, Yazd, Iran
Sanaz Akbarzadeh - Department of textile engineering, Science and Research Branch, Islamic Azad University, Yazd, Iran
Soheila Ghaemi - Department of textile engineering, Science and Research Branch, Islamic Azad University, Yazd, Iran

One of the bioactive flavonoid compounds, which is present in enormous amounts in plants, is hematoxylin [1]. Hematoxylin is widely used as a biological stain in biomedical researchlaboratories and diagnostic procedures [2]. In the present work we will report the electrochemistry and electrocatalytic activity of the hematoxylin modified carbon paste electrode Purpose of research Among all the carbon electrodes, the carbon paste electrode (CPE) is an appealing and widelyused electrode material in the fields of electrochemistry, electro analysis, etc. due to its attractive advantages, such as simple preparation, low-cost implementation, renewability, low background current, and wide potential window [4]. In the current study, the preparation of hematoxylinmulti-wall carbon nanotubes (HMWCNT) modified carbon paste electrode (CPE) and its application for the electrocatalytic oxidation of hematoxylin have been reported [5]. In order to construction of electrode, amount of MWCNT and MIP, also solution pH and time ofhematoxylin accumulation on MIP–MWCNT–CPE was optimized. Fig.1 shows the voltammograms of different CPE electrode with different composition.Method Finally, a suitable method for determination of hematoxylin was presented. Molecularly imprinted polymer (MIP) were synthesized of hematoxylin (template), methacrylic acid as functional monomer, ethylene glycol dimethacrylate as cross-linking agent and 2,20- azobisisobutyronitrile as initiator. Then the MIP were used to modify the carbon paste electrode (CPE) [6]. ConclusionCharacterization of MIP was done with FTIR and the modified electrode demonstrated withcyclic voltammetry (CV) and differential pulse voltammetry (DPV), and impedance analysis thatthe modified electrode is responsive towards the target molecule. A linear range of peak current in (DPV) was obtained over 7.0- 500 nM with the limit of detection of 2.8 nM.

Hematoxylin, Carbon paste electrode, molecularly imprinted polymer, Multiwall carbon nanotube