Electrochemical Characterization of Au/ZnO/PPy/graphene nanocomposite and its application for simultaneous determination of ascorbic acid (AA), epinephrine (EP) and uric acid (UA)

Metal nanoparticles due to the unique electrical, magnetic and optic properties have been taken highly into consideration [1]. Polymer materials were used extremely for making sensors, within recent decade. One of advantages of polymers is that they may be synthetized on various beds such as graphene, carbonnanotube, gold [2]. Using quick, easy, sensitive and precise methods for simultaneous measurement of some chemical compounds is highly important [3]. Here, we report sensor based on graphene oxide/ polypyrrole/zinc oxide (ZnO)/Au nanoparticles nanocomposite modified glassy carbon electrode (GO/Ppy/ZnO/Au GCE) for simultaneous determination of ascorbic acid (AA), epinephrine(EP) and uric acid (UA). The morphology andstructure of GO/Ppy/ZnO nanocomposites were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared (FT-IR). The GO/Ppy/ZnO/Au, GCE-based sensor exhibited excellent electrocatalytic activity and high stability fordetermination of AA, EP and UA. The prepared electrode separates the oxidation peak potential of AA-EP by 90 mV, and EP-UA by 210 mV, while the bare GCE cannot resolve them. The electrochemical sensor shows a wide linear response and detection limit was found to be 100, 50and 70 nM for AA, EP and UA respectively. In addition, the proposed sensor shows good selectivity and stability along with good precision and consistency.

کلیدواژه ها:

ascorbic acid ، Epinephrine ، uric acid ، nanoparticles ، Simultaneous determination