Molecular Interactions of lncRNAs: Cellular Fate Determination and Tissue Regeneration

LncRNAs (long non-coding RNAs), defined as non-coding RNAs with length ≥200 nt, are responsible to control the degradation process, RNA stability, orchestration, inhibition, transcription and histone modification etc. These RNAs have been termed as the key agents of several vital mechanisms such as development, organogenesis and regeneration of damaged tissues etc. They interact with a number of partner molecules either proteins, RNAs or DNAs. They also control the cellular behaviour of stem cells such as differentiation or self-renewal or their paracrine effects. This editorial is discussing the significance of lncRNAs as therapeutic target in stem cell therapy field

کلیدواژه ها:

LncRNAs ، Regeneration ، Molecular interactions ، Stem cell fate ، Differentiation