The relationship between clinicobiochemical markers and depression in women with polycystic ovary syndrome
- سال انتشار: 1393
- محل انتشار: International Journal of Reproductive BioMedicine، دوره: 12، شماره: 12
- کد COI اختصاصی: JR_IJRM-12-12_004
- زبان مقاله: انگلیسی
- تعداد مشاهده: 551
نویسندگان
Research Center of Behavioral Sciences and Dependency, Hamedan University of Medical Sciences, Hamedan, Iran
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA.
Department of Obstetrics and Gynecology, Hamedan University of Medical Sciences, Hamedan, Iran.
Department of Community Medicine, Hamedan University of Medical Sciences, Hamedan, Iran
چکیده
Background: Previous studies have demonstrated that clinical features of 16TPolycystic ovary syndrome16T (PCOS) are associated with a lower degree of health, self, and sex satisfaction.Objective: Our study aimed to investigate possible associations between depression and different clinicobiochemical markers of PCOS.Materials and Methods: In a cross-sectional analytic study, 120 PCOS women aged 18-45 yr, were enrolled. Beck Depression Inventory was used to assess depression. Also, all participants underwent biochemical studies. Individuals with 15 points and more in Beck test were referred to a psychiatrist to participate in a complementary interview for the diagnosis of depression based on Diagnostic and Statistical Manual of Mental Disorders IV (DSMIV-TR) criteria.Results: Among the study participants, 82 women (68.3%) were non-epressed, and 38 patients (31.7%) had some degrees of depression. According to the psychiatric interview, 10 patients (8.3%) had major depression, 22 patients (18.3%) had minor depression and 6 patients (5%) had dysthymia. We failed to show any significant difference in body mass index, hirsutism, infertility, serum total testosterone, lipid profile, and the homeostasis model assessment of insulin resistance (HOMA-IR) between depressed and non-depressed subjects (p> 0.05). Using Spearman correlation, we did not find a positive correlation between BDI scores and clinicobiochemical markers for all PCOS subjects (-0.139≤r≤+0.121, p> 0.05).Conclusion: In spite of high rate of depression in women with PCOS, there was no significant association between Clinicobiochemical Markers and depression.کلیدواژه ها
16TPolycystic ovary syndrome, Depression, Obesity, Hirsutism, Complicationاطلاعات بیشتر در مورد COI
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