Zahedi - Simulation and AI Research Center, Department of Chemical Engineering, Razi University , Kermanshah, Iran
Ali Elkamel - Department of Chemical Engineering, University of Waterloo, Ontario, N۲L ۳G۱, Canada
Monjezi - Simulation and AI Research Center, Department of Chemical Engineering, Razi University , Kermanshah, Iran

The extraction of nimbin from neem seeds using supercritical carbon dioxide is investigated in this paper. A model that accounts for intraparticle diffusion (De) and external mass transfer of nimbin (kf) is presented for the supercritical extraction process. The following range of conditions: 0.24– 1.24cm3/min of CO2, 10–26MPa, 308–333K, 1.0–2.5g of neem kernel powder and 0.0575–0.185cm of particle size of neem kernel powder, were considered. Proposed model was solved numerically and results were successfully validated with experimental data.

Nimbin; Neem seeds; Supercritical CO2; Mass transfer; Modeling