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Prediction Of Local Measurements Of Cell Viscoelasticity With Fractional Calculus Approach

عنوان مقاله: Prediction Of Local Measurements Of Cell Viscoelasticity With Fractional Calculus Approach
شناسه ملی مقاله: NSOECE03_060
منتشر شده در سومین کنفرانس بین المللی رویکردهای نوین در علوم ،مهندسی و تکنولوژی در سال 1394
مشخصات نویسندگان مقاله:

Mohammad Amirian Matlob - Student at Tabiat Modares University, Department of Mathematical Sciences,iran
Yousef Jamali - An Assistant Prof at Tabiat Modares University, Department of Mathematical Sciences,iran

خلاصه مقاله:
Investigation of the cell behavior under deformation is crucial. For instance, we can refer to cancer cells that have different mechanical properties from healthy cells. Cancer is a disease in which many of the characteristics of normal cell behavior are lost or perturbed. Studies has indicated that in the cancer cells, microtubules and microfilaments properties will be changed. Microfilaments or actin filaments are the thinnest filaments of the cytoskeleton, a structure found in the cytoplasm of eukaryotic cells. These linear polymers of actin subunits are flexible and relatively strong, resisting buckling by multi-piconewton compressive forces and filament fracture by nanonewton tensile forces. Consequently the cells elasticity under deformation will have different behavior from the healthy cells. As a result of our research, in this paper we have represented a new fractional derivative constitutive model for cell viscoelasticity; that has more accuracy than the other suggested models. Finally, we claim proposed model can be suitable replacement for Bausch model in cell viscoelasticity prediction.

کلمات کلیدی:
fractional calculus, cell viscoelasticity, modelling, cell biomechanics

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/449321/