Study the Effect of Ethanol Extract of Achillea, Green Tea and Ajowan on Pseudomonas Aeruginosa

Objective: Infections are increasing caused by antibiotic-resistant Pseudomonas aeruginosa day by day. For this reason, many researchers have tried to find new compounds as alternative antibiotics. The purpose of this study was to evaluate the effect of yarrow extract, green tea and Ajowan on Pseudomonas aeruginosa. Methods: Extraction of Achillea, green tea and Ajowan was done with rotary. For this study, 12 strains of Pseudomonas aeruginosa isolated from patients in the city of Zabol. Minimum inhibitory concentrations of the plant extract of Achillea, green tea and Ajowan wasdetermined in different concentrations by dilution on bacteria with plate method. Results: Results from plant extracts showed the highest MIC (minimum inhibitoryconcentration) of green tea extract was concentration of 2.5 milligrams per milliliter for Pseudomonas aeruginosa that 8 strains were inhibited at this concentration. Also, Thehighest inhibitory concentration (MIC) of achiella extract against strains of seudomonas aeruginosa was 5 milligrams per milliliter that four strains were inhibited at this concentration, the lowest concentration of inhibitor was 62 milligrams per milliliter.Discussion : This study showed that Achiella, green tea and Ajowan have antibacterial effect against strains of Pseudomonas aeruginosa. However, the clinical use of these plants require more and wider research.

کلیدواژه ها:

Pseudomonas ، aeruginosa ، Extract ، green tea ، Ajowan ، ، Achiella ، Minimum inhibitory ، concentration (MIC) ،