D.A Adekomi - Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria- Department of Anatomy, College of Medicine and Health sciences, Afe Babalola University, Ado, Ekiti State, Nigeria
A.M Afodum - Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria
K.K Quadri - Department of Physiology, University of Lagos, Lagos, Nigeria
T.D Adeniyi - Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun Stat, Nigeria

The aim of this investigation was to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old) were randomly assigned into two groups; A and B. Aqueous extract of S. officinalis leaves (300 mg/kg body weight) was administered orally to the rats in group B while the rats in group A received equal volume of normal saline for 14d. At termination of treatment, the histopathology of the kidney and liver were assessed. The kidney and the liver in the extract treated rat displayed organized and preserved histological profile. Our findings suggest that S. officinalis has no deleterious effects on the kidney and liver of the rats.

Kidney, Liver, Normal saline, Histopathology, prague-Dawley Rats