Increasing of serumnitric oxidemetabolites in chicken Eimeria infection

In order to determine the involvement of nitric oxide in the pathogenesis of coccidiosis induced by , 30 chickens were challenged with mixed four species of (E. acervulina, E. maxima, E.necatrix, E. tenella and ) Histopathological examination revealed a loss of epithelial tissue, congestion of blood vessels, severe muscular edema and necrosis of submucosa. The sum total of nitrite and nitrate was increased in the serum at 6, 10 and 14 days post-infection progressively, but was only significant ( < 0.05) at 10 and 14 days post-infection compared to earlier days. The nitrate amounts were also significantly higher at days 10 and 14. It can be concluded that infection by four species of stimulated NO production after infection. It is therefore possible thatNOis involved in the pathogenesis of coccidiosis

کلیدواژه ها:

Nitrite and nitrate ، coccidiosis ، Eimeria ، chicken