C3 and C4 Complement Levels in Iron Deficiency Anemia

  • سال انتشار: 1390
  • محل انتشار: فصلنامه آسیب شناسی ایران، دوره: 6، شماره: 2
  • کد COI اختصاصی: JR_IJP-6-2_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 1133
دانلود فایل این مقاله

نویسندگان

Mohammad Hadi Sadeghian

Dept. of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran

Mohammad Reza Keramati

Neonatal Research Center, Mashhad, Iran

Hossein Ayatollahi

Dept. of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran

Houshang Rafatpanah

Dept. of Immunology, Immunology research center, Mashhad, Iran

چکیده

Background and Objectives: Complement proteins are some of the most important plasma proteins of the innate immune system. Impaired immune function is reported in subjects who areiron deficient, and there are documents that these patients are prone to infection. This study wasconducted to show whether serum C3 and C4 complement change in adult nonpregnant female with iron deficient anemia or not. Methods: Forty five normal subjects and 45 iron deficient anemia (hypochrom microcytic) cases were entered in this case and control study by using patients’ clinical history and also results ofCBC, Serum ferritin, iron and total iron binding capacity. Serum C3, and C4 were measured in case and control subjects with nephlometry method, finally comparison between result of patients group and control group was done with using suitable statistical test.Results: Mean serum C3 and C4 in patient group was 1.28 ± 0.81 and 0.28 ± 0.23 g/L respectively and for control group was 1.39 ± 0.87 and 0.35 ± 0.25 g/L respectively. Although serum complementswere slightly lower in patient groups in compared to control group but this differences was notmeaningful with t test. Conclusion: This study showed serum C3 and C4 complements levels were not changed in iron deficiency anemia.

کلیدواژه ها

Iron Deficiency Anemia, C3 Complement, C4 Complement

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.