Cytodiagnosis of Cutaneous Basal and Squamous Cell Carcinoma

سال انتشار: 1386
محل انتشار: فصلنامه آسیب شناسی ایران، دوره: 2، شماره: 3
کد COI اختصاصی: JR_IJP-2-3_003
زبان مقاله: انگلیسی
تعداد مشاهده: 702

نویسندگان

Dept. of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran

Dept. of Dermatology, Mashhad University of Medical Sciences, Mashhad, Iran

چکیده

Background and Objective: Cutaneous cytology is the study of scraping or smears obtained from skin lesions. Although not commonly employed, cutaneous cytology has been a useful tool forclinicians due to simplified procedures and high sensitivity and specificity of presurgical clinical diagnosis of common types of skin tumors. This investigation was conducted to study usefulness of cutaneous cytology in diagnosis of basal and squamous cell carcinoma.Methods: We collected 42 skin tumors in total, clinically presumed to be either BCC (n = 31) or SCC (n = 10). Samples were taken by the scraping technique. After smearing the cells onto severalglass slides, they were fixed with 96% alcohol. The specimens were stained with Papanicolaou stain.Punch biopsies were taken to confirm the clinical and cytologic impression. Results: Cytodiagnosis and histopathologic examination of 42 cases of BCC (n = 32) and SCC(n = 10) showed a significant concordance between histopathology of skin specimen and cytologicdiagnosis with a sensitivity rate of 96.8% and specificity rate of 90% and with a high positive predictive value of 96.8%.Conclusion: Cytologic examination is easy to perform, saves time, and provides a rapid and reliable procedure in diagnosis and confirmation of non-melanoma malignant skin tumors (BCC and SCC).

کلیدواژه ها

Skin, Cytology, Basal cell carcinoma, Squamous cell carcinoma

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