Digital Organism Simulation Environment (DOSE): A Library for Ecologically-Based In Silico Experimental Evolution
سال انتشار: 1392
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 595
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شناسه ملی سند علمی:
JR_ACSIJ-3-1_007
تاریخ نمایه سازی: 24 فروردین 1393
چکیده مقاله:
Testing evolutionary hypothesis in biological setting is expensive and time consuming. Computer simulations of organisms (digital organisms) are commonly used proxies tostudy evolutionary processes. A number of digital organism simulators have been developed but are deficient in biologicaland ecological parallels. In this study, we present DOSE (Digital Organism Simulation Environment), a digital organism simulator with biological and ecological parallels. DOSEconsists of a biological hierarchy of genetic sequences, organism, population, and ecosystem. A 3-character instruction set thatdoes not take any operand is used as genetic code for digital organism, which the 3-nucleotide codon structure in naturallyoccurring DNA. The evolutionary driver is simulated by a genetic algorithm. We demonstrate the utility in examining the effects of migration on heterozygosity, also known as local genetic distance
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نویسندگان
Clarence FG Castillo
School of Information Technology, Republic Polytechnic Singapore, Republic of Singapore
Maurice HT Ling
School of Chemical and Biomedical Engineering, Nanyang Technological University Singapore, Republic of Singapore Department of Zoology, The University of Melbourne Parkville, Victoria ۳۰۱۰, Australia